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TLR AGONISTS

Novel Injectable Formulations


  • Novel formulations allow for localization of a drug’s effects, improving vaccine efficacy
  • Prodrugs of IRMs show limited systemic exposure and cytokine release
  • These compounds show enhanced adjuvant action as measured by increased CTL and Th1 activation
  • Formulating IRMs to give depot effect also enhances vaccine efficacy and systemic tolerability

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EXHIBITIONS AND CONFERENCES

December 9 - 13, 2009
Drug Delivery to the Lungs
Edinburgh, UK

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