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TLR AGONISTS

Conjugates and Combinations


Molecules that can be conjugated to antigen

Conjugation can lead to enhanced vaccine efficacy while decreasing systemic side effects.

  • S-36212 is the lead compound
  • Number of follow-on compounds with different functionality for conjugation
  • Conjugation has been shown to enhance immunogenicity of vaccines by demonstrating increased antibody responses as well as increased Th1 and CTL responses in both mice and primates

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