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Challenging formulations and cosmetic appearance can have a significant impact on your choice of components. To help you design the right transdermal system, we offer a wide variety of backings, liners, membranes and tapes, along with customer and technical service support designed for your long term success. Start now with the Component Comparison & Selection Guide to help you make the right decisions for your product.
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Explore 3M Components
We offer a wide variety of transdermal component options:
Liners | Backings | Membranes | Tapes
Component Comparison & Selection Guide
Want to explore the variety of transdermal patch components? Need help choosing the right components for your application? This step-by-step guide can help.
The release liner protects the adhesive and drug formulation. It is removed prior to patch application. Important considerations when choosing a liner include adhesive and drug formulations and release force.
3M Scotchpak™ Fluoropolymer Coated Release Liners
provide a premium, smoother release from a wide variety of skin contact adhesives. These include silicone, acrylate, polyisobutylene (PIB) and rubber-based adhesives. Compatible with many formulations, Scotchpak liners have excellent chemical stability and a long shelf life.
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The backing is the outermost layer of the patch, which protects the formulation while the patch is being worn. Important considerations include occlusivity, patient comfort, and cosmetic appearance. 3M offers a wide variety of backing materials to help ensure suitability, stability and a successful final product.
3M Scotchpak™ Backings.
These polyester-based laminates provide disparate properties in a single web. No solvents or adhesives are used in 3M’s proprietary lamination process, thereby minimizing the potential for drug and/or excipient interactions.
3M CoTran™ Backings.
This broad backing portfolio contains translucent and pigmented monolayer films providing low moisture and high oxygen transmission, and nonwoven fabrics providing both high moisture and oxygen transmission. These properties are important considerations as you design your patch for optimal patient comfort over the patch wear duration.
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In multi-layer and reservoir patch systems, the membrane controls the rate of diffusion of the drug out of the patch and into the skin. Important properties to consider include the membrane composition and thickness. 3M offers a wide variety of ethylene vinyl acetate membranes for use in TDD systems.
3M CoTran™ Membranes feature:
- Flexibility, for optimal patient comfort
- An extensive history of use & excellent track record of safety
- Excellent adhesive anchorage
- Superior film quality, due to the melt-cast manufacture process & tight caliper control
- Manufactured under cGMP conditions
Specific surface textures of these membranes improve both web handling and bonding between the membrane and the adhesive. These films are offered in a range of vinyl acetate content and caliper, to meet your unique needs.
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Tapes are protective patch coverings that provide good skin adhesion over the wear duration and stabilization to your patch system. Our tape components are part of 3M’s family of medical tapes, which can be found in hospitals and clinics around the world, where they have been tried, tested and trusted for decades.
- Nonwoven tapes. Excellent conformability and breathability.
- Foam tapes. Soft and cushioning, yet conformable.
Both options allow for easy placement, good adhesion, and extended wear – up to 7 days.
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From beginning to end, we support your custom TDD solution every step of the way. From selecting a product for your formulation, to selecting the right components, to providing documentation packages for regulatory filings—3M is there. And with 30 years of transdermal experience and more than a century in business, you can trust that 3M will continue to be a solid partner for the life of your project.
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