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Hollow Microneedle Technology

Learn more about 3M hMTS for preclinical studies.

Take Drug Delivery to New Levels

Hollow microneedle devices offer exciting benefits to both patients and drug providers. With the comfort of a patch and the efficiency of a syringe, 3M Hollow Microstructured Transdermal Systems (hMTS) may improve the patient experience. This delivery option can also offer significant market differentiation in the crowded market.

In addition to the 3M hMTS kit for human factors studies, a hollow microneedle device for customers interested in preclinical studies is now available.
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Increase Patient Compliance

Millions of people require injectable treatments, but an estimated 10% avoid treatment due to needle phobia. Hollow microneedles are designed for efficient delivery of liquid formulations, including antibodies and hormones, into the skin (0.5 mL to 2 mL) via a hollow microneedle array. Many patients find this approach less intimidating than syringes or pens.

By reducing anxiety, microneedle delivery may improve patient compliance in some patient groups. Better compliance means patients can have more good days and enjoy a better quality of life.


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Hollow microneedle benefitsImprove Product Effectiveness
While drug PK profiles need to be evaluated on an individual basis, hollow microneedle delivery may offer many benefits when compared with conventional injections:

  • Faster absorption
  • Higher bioavailability of some therapies
  • Higher peak blood levels


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Stay at the Leading Edge

Gain a competitive edge when you partner with the expert in microneedle technology. For over 50 years, 3M has created innovative solutions for the pharmaceutical industry. Our product development and manufacturing specialists will work with you from start to finish, to create a hollow microneedle solution that gives you a competitive edge.

  • Expertise in customizing solutions to fit drug formulation needs
  • Secure supply chain with regulatory, global compliance & toxicology support from world class laboratories
  • Dedicated process technology center to mitigate production risk when transferring complex products
  • Start-to-finish services to develop & commercialize your innovation
  • Global manufacturing capabilities that cover everything from clinical trials to full-scale commercial production and distribution
  • Design based on human factors studies for dexterity-challenged patients

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Get Started

Learn about our clinical data findings, and discover how hollow microneedle technology and 3M can help you meet your strategic goals. Contact Us


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Related Posters, Presentations and Publications

3M Hollow Microneedle System Brochure (249 kb, PDF)

Hollow Microneedle Delivery - Innovation Pointing the Way (1,181 kb, PDF)

3M Drug Delivery Systems - Intradermal Delivery of Biologics

Patient Demand, Vaccines, And Drug Delivery: Q&A With Steve Wick Of 3M Drug Delivery Systems

3M Hollow Microstructured Transdermal System Human Factors Kit (727 kb, PDF)

Poster: Rapid Intradermal Delivery of Liquid Formulation Using a Hollow Microstructured Array (435 kb, PDF)

Poster: A Hollow Microstructured Transdermal Delivery (hMTS) for Needle-Free Delivery of Biopharmaceuticals (14.44 mb, PDF)

Intradermal Delivery of a Methylene Blue using hMTS for Sentinal Lymph Node Mapping (670 kb, PDF)

Hollow Microneedle Delivery of a Therapeutic Dose of Methotrexate and Humira® Advantages of Intradermal Delivery Over Conventional Routes (844 kb, PDF)

High Volume Intradermal Delivery in Humans Using a Fully Integrated Hollow Microneedle Device (716 kb, PDF)

Intradermal Delivery of Liquid Formulation Using a Hollow Microstructured Array (435 kb, PDF)

A Hollow Microstructured Transdermal System (hMTS) for Needle-Free Delivery of Biopharmaceuticals (64.1 mb, PDF)

CONTACT US

Looking for the right drug delivery partner? Look to 3M.
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