The Empore membrane is available in two different densities. Standard density membranes are recommended for almost all applications. High density membranes should be reserved for clean sample matrices.
Membrane Formats
Empore Extraction Disk Products are available in two membrane formats:
- Standard Density (SD)
- Improved flow characteristics
- Optimized for biological matrices
- Contains standard (47µm) particle size sorbents
- Accommodates a wide range of sample types and volumes
- High Density (HD)
- Maximum extraction efficiency/minimal elution volumes
- Contains small (12 µm) particle size sorbents
- For cleaner sample matrices, minimal elution volumes
Both SD and HD membrane formulations are made by entrapping sorbent particles within an inert matrix of polytetrafluoroethylene. The resulting particle-loaded membrane (90% particles: 10% PTFE, by weight) results in a denser, more uniform extraction bed than can be achieved in a traditional SPE cartridge made from loosely packed particles.
Membrane Formats |
Standard density (SD) Empore disk (47 µm particle size) |
High density (HD) Empore disk (12 µm particle size) |
High Performance
The dense particle packing and uniform distribution within SD and HD Empore disks offer efficiency and reproducibility. The diffusion distances between particles is minimized, adsorption is more efficient, and extraction can be accomplished using less sorbent mass to provide the following performance gains:
- minimized solvent volumes
- higher throughput
- small elution volumes
- reduced time for, or elimination of, the evaporation step
For additional information on HD and SD products (PDF, 686 Kb)
