The fundamental basis of the Empore Disk technology is the ability to create a particle-loaded membrane, or disk, using any sorbent particle. The particles are tightly held together within an inert matrix of polytetrafluoroethylene (90% sorbent: 10% PTFE, by weight). The PTFE fibrils do not interfere with the activity of the particles in any way. The Empore membrane fabrication process results in a denser, more uniform extraction medium than can be achieved in a traditional Solid Phase Extraction (SPE) column or cartridge prepared with the same size particles. This process can be further manipulated to create membranes of different densities.
The Empore Disk is a particle-loaded membrane. This membrane can be secured into a variety of devices that offer advantages compared to other SPE technologies, such as particles packed loosely in columns or glass fiber disks. Unique features of the Empore Membrane format include:
SPE is a procedure in which an analyte is isolated and concentrated from a liquid sample. It is also described as a clean-up procedure that prepares the analyte prior to analysis so that the desired sensitivity range of an analytical method can be obtained. Analytes are isolated from complex mixtures by proper selection of a variety of sorbent chemistries (reversed phase, mixed phase, normal phase, and ion exchange).