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Technology
The fundamental basis of the Empore Disk technology is the ability to create a particle-loaded membrane, or disk, using any sorbent particle. The particles are tightly held together within an inert matrix of polytetrafluoroethylene (90% sorbent: 10% PTFE, by weight). The PTFE fibrils do not interfere with the activity of the particles in any way. The Empore membrane fabrication process results in a denser, more uniform extraction medium than can be achieved in a traditional Solid Phase Extraction (SPE) column or cartridge prepared with the same size particles. This process can be further manipulated to create membranes of different densities.
Poly(Styrene Divinylbenzene)
Bonded Silica
The Empore Disk is a particle-loaded membrane. This membrane can be secured into a variety of devices that offer advantages compared to other SPE technologies, such as particles packed loosely in columns or glass fiber disks. Unique features of the Empore Membrane format include:
- Uniform, dense packing of sorbent particles
- Inert (PTFE) supporting matrix
- Clean eluates for analysis by mass spectrometry
- More efficient mass transfer kinetics
The thin bed mass of the disk allows for these performance gains:
- minimized solvent and sample volumes
- high throughput
- small elution volumes
- ability to eliminate the evaporation step
- sample processing at maximal flow rates without channeling
- consistent recoveries
SPE is a procedure in which an analyte is isolated and concentrated from a liquid sample. It is also described as a clean-up procedure that prepares the analyte prior to analysis so that the desired sensitivity range of an analytical method can be obtained. Analytes are isolated from complex mixtures by proper selection of a variety of sorbent chemistries (reversed phase, mixed phase, normal phase, and ion exchange).
The general procedure for SPE is outlined below.
3M Empore TM Products
3M Purification, Inc.
3130 Lexington Avenue South
Eagan, MN 55121
USA
Phone: 1-888-509-5330
Fax: 1-651 789-3455
CUNO
300 Tartan Drive
London Ontario N5V 4M9
Phone: 800-265-1840
Fax: 519-452-6286
3M Deutschland GmbH
3M Purification
Carl - Schurz - Straße 1
41453 Neuss
Germany
Phone: +49 (0) 2131 - 145153
Fax: +49-(0)2131-14-5100
Email
Health Care Division
3M Hong Kong limited
5/F, Victoria Centre,15 Watson
Road, North Point, Hong Kong
Phone: 2806 6111
Fax: 2347 7102
CUNO
Sumitomo 3M Limited
33-1, Tamagawadai 2-Chrome
Setagaya-ku, Tokyo, 158-8583
Japan
Phone: +81-3-3709-8638
Fax: +81-3-3716-7495
Website
3M Korea Limited
27-3, 20th Floor, Daehan Investment Security B/D.
Yoido-dong, Youngdeungpo-Gu, Seoul City
Korea
Phone: +82-2-3771-4197
Fax: +82-2-780-3650
3M Technologies (S) Pte Ltd.
1 Yishun Avenue 7
Singapore 768923
Phone: 65 6450 8888
Fax: 65 6552 2116
Email
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