Peridex™ Chlorhexidine Gluconate 0.12% Oral Rinse Refill, 1 - 16 oz bottle, 12132

∙ The clinical significance of Peridex oral rinse's antimicrobial activities is not clear.
∙ Three months after Peridex oral rinse was discontinued, the number of bacteria in plaque had returned to baseline levels and resistance of plaque bacteria to chlorhexidine gluconate was equal to that at baseline. Clinical effectiveness and safety of Peridex oral rinse has not been established in children under age 18.
∙ Peridex oral rinse is indicated for use between dental visits as part of a professional program for the treatment of gingivitis. Patients with a known sensitivity to chlorhexidine gluconate should not use Peridex oral rinse. The effect of Peridex oral rinse on periodontitis has not been determined. Common side effects associated with the use of Peridex oral rinse include an increase in the staining of oral surfaces, an increase in calculus formation, and an alteration in taste perception. Please see page 18 for full prescribing information.
∙ Source: FDA Consumer Magazine, May∙ June 2002.