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At 3M, we are advancing the global biopharmaceutical industry by helping to build better and more efficient manufacturing processes, improving product safety by providing tools for monitoring and tracking, and reducing energy usage with our technologies.

Filtration Products for the Biopharmaceutical Industry

Zeta Plus™ Encapsulated System

Zeta Plus™ Encapsulated System

Single-Use Solutions for Cell Culture Clarification

3M offers a complete package of single-use systems for cell culture clarification applications for biopharmaceutical customers. Single-use Zeta Plus™ Encapsulated depth filter clarification solutions are available in scaleable capsule formats from R&D to process development to pilot / clinical production to commercial and large scale production.

LifeASSURE™ PDA Series Filters — The Preferred Membrane For Biopharmaceutical Applications

LifeASSURE™ PDA Series Filters — The Preferred Membrane For Biopharmaceutical Applications

In addition to sterile filtration prior to the final filling step, sterilizing filters are used in many intermediate steps to reduce cross-contamination risk from in-process liquids such as buffers. Since biopharmaceutical unit operations are discontinuous in nature, elution pools (e.g. Protein A pool) need to be filtered with 0.2 µm filters prior to storage in order to manage bioburden loads. To prevent growth of microorganisms in downstream chromatography steps, post depth filter permeate is filtered using 0.2 µm sterilizing or bioburden reduction grade filters.

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