Clinpro™ Tooth Crème 0.21% w/w Sodium Fluoride Anti-Cavity Toothpaste is an advanced formula containing an innovative tri-calcium phosphate ingredient and is available exclusively from 3M ESPE. The optimized formula makes Clinpro Tooth Crème an outstanding choice. It contains fluoride as well as calcium and phosphate, which are components naturally found in saliva.
This proprietary formula successfully integrates these components, enhancing, rather than compromising, the product’s performance. During the manufacturing process, a protective barrier is created around the calcium allowing it to coexist with the fluoride ions. Think of this as a bubble that transports the Tri-Calcium Phosphate to the teeth. As the toothpaste comes in contact with saliva during brushing, the barrier breaks down and makes the calcium, phosphate and fluoride readily available to the tooth. The tooth naturally absorbs these components, helping to prevent the initiation and further progression of demineralization and allowing remineralization to occur. The illustration below shows this system in action.

Saliva activates the calcium compound, breaking down the protective coating and making it available to the tooth. Practicing dental professionals and industry experts alike will discover the breakthrough benefits of this winning formula. Your patients should, too. The toothpaste that makes every brush better, Clinpro Tooth Creme, is now available.
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Product Information |
Summary of Advantages:
- Delivers more fluoride to the tooth
- Strengthens teeth
- Reverses white spots
- Prevents cavities
- Reduces root cavities
- Contains 0.21% w/w (950 ppm fluoride ion)
- Contains an innovative calcium and phosphate ingredient
- Gentle, effective cleaning
- Cleans and whitens teeth
- Low abrasion
- Replaces conventional toothpaste regimen
- Available in a convenient 113g flip-top tube
- 2 year shelf life
Fluoride Uptake |
% Change in Surface |
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| Clinpro™ Tooth Crème 0.21% w/w Sodium Fluoride Anti- Cavity Paste improves fluoride delivery to the tooth |
Clinpro™ Tooth Crème 0.21% |
* 3M internal data on file.
Important Patient Information
What is Clinpro Tooth Crème 0.21% w/w Sodium
Fluoride Anti-Cavity Paste?
Clinpro Tooth Crème contains fluoride as well as calcium and
phosphate, which are components naturally found in saliva.
It is used to prevent tooth decay and can be used in place of
your usual toothpaste.
How do I use Clinpro Tooth Crème?
- Place a pea-sized amount of Clinpro Tooth Crème on a
soft-bristled toothbrush and brush teeth for at least two
minutes. - After brushing rinse out your mouth with water and spit out.
- Use twice daily or as directed by your dental professional.
- The optimal time to brush with Clinpro Tooth Crème is
first thing in the morning and just prior to going to sleep.
Children under 6 years of age:
- To be used only on the advice of a dental professional.
- Clinpro Tooth Crème should only be used under direct
adult supervision. - Use only a pea-sized amount.
- After brushing, your dental professional recommends:
- - Spit out without rinsing with water.
- - Spit out and rinse thoroughly with water.
- Do not swallow.
- Use twice daily or as directed by your dental professional.
- The optimal time to brush with Clinpro Tooth Crème is
first thing in the morning and just prior to going to sleep.
Where should I go for more information about Clinpro
Tooth Crème?
- Talk to your dental professional or your healthcare
provider.
Always read the label and use as directed. Keep out of reach of children
under 6 years of age. Repeated swallowing of high levels of fluoride may
cause chalk-like, lacy markings on teeth (dental fluorosis). For this reason,
children with baby teeth (developing dentition) require adult supervision to
minimise or prevent swallowing of excessive amounts.

